Principals
| Bro Liefroy (Antoine Bajon)* | 1852 - 1862 |
| Bro Gregory (John Conolly)* | 1862 |
| Bro Botthian | 1863 - 1864 |
| Bro Lothaire Marie (Antoine Combes)* | 1864 - 1871 |
| Bro Sagittaire (Jean Joseph Caille) | 1871 - 1881 |
| Mr H B Collinge (Supervisor) | 1881 - Dec 1885 |
| Bro Lothaire Marie (Antoine Combes) | Dec 1885 - Jul 1888 |
| Bro Ephrem Leander (Bartholomew Sharkey) | Jul 1888 - Jul 1889 |
| Bro Sumund Augustine (Arayneau Auguste) | Jul 1889 - Nov 1893 |
| Bro Dolet Eugene (Eugene Christophe Le Moal) | Nov 1893 - Feb 1894 |
| Bro Patrick of Jesus (Peter Felix Nelson) | Feb 1894 - Mar 1896 |
| Bro Osmund Gregory (Thomas James McGrath) | Mar 1896 - Apr 1899 |
| Bro Ascisclus Michael (Edward Joseph Noctor) | Nov 1900 - Mar 1914 |
| Bro Aimare Pierre Sauron (Acting) | Aug 1907 - Jun 1908 |
| Bro Stephen Edward (Malachy Buckley) | Apr 1914 - Apr 1921 |
| Bro Aimare Pierre (Pierre Sauron) | Apr 1921 - Feb 1922 |
| Bro Marcian James (James Joseph Cullen) | Feb 1922 - Apr 1927 |
| Bro Stephen Edward (Malachy Buckley) | Apr 1927 - Dec 1933 |
| Bro Vernier Auguste (Louis Clerc) | Jan 1934 - Feb 1936 |
| Bro Dominic John (Philip James Walsh) | Mar 1936 - Jul 1937 |
| Bro Stephen Edward (Malachy Buckley) | Jul 1937 - Jun 1939 |
| Bro Flannan Paul (Bernard Neil Gallagher) (Acting) | Jun 1939 - Aug 1939 |
| Bro D Joseph (James Francis Brophy) | Sep 1939 - Apr 1947 |
| Bro Canice Joseph (Jerome Brennan) | Apr 1947 - Sep 1947 |
| Bro Stephen Anthony (John Gerard Knoll) | Sep 1947 - Jan 1950 |
| Bro Flannan Paul (Bernard Neil Gallagher) | Jan 1950 - Dec 1950 |
| Bro Ulric Ignatius (Patrick Barry) | Jan 1951 - Dec 1956 |
| Bro Lawrence Henry (Stephen Lawrence Robless) | Jan 1957 - Dec 1963 |
| Bro Justinian of Mary (Justinian Lawrence de Souza) | Jan 1964 - Dec 1966 |
| Bro Ildephonsus Patrick (Andrew Martin Loh) | Jan 1967 - Jun 1974 |
| Bro Joseph Patrick Kiely | Jun 1974 - Dec 1978 |
| Bro Kevin Byrne | Jan 1979 - Dec 1991 |
| Bro Paul Anthony Rogers | Jan 1992 - Sep 1997 |
| Mr Benjamin Lui Seng Cheong | Sep 1997 - Dec 2008 |
| Dr Koh Thiam Seng | Jan 2009 - Dec 2015 |
| Rev Fr (Dr) Adrian Augustus Danker, SJ | Jan 2016 - Dec 2021 |
| Mr Justin Arul Pierre | Jan 2022 - present |
* One of the six pioneer Brothers who arrived in 1852.
